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Basic Info. Setmelanotide (trade name IMCIVREE) is a medication used for chronic weight management in individuals with obesity caused by genetic conditions affecting the melanocortin-4 receptor (MC4R) pathway. Specifically, it's approved for individuals with obesity due to deficiencies in proopiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1 (PCSK1), or leptin receptor (LEPR), as well as Bardet-Biedl syndrome (BBS). ...
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Basic Info. Vesugen is a bioregulator and geroprotective tripeptide. Research has shown it to protect the vascular system from the effects of aging by limiting the development of atherosclerosis and decreasing overall endothelial cell dysfunction. Systems that are sensitive to vascular damage and decline therefore show the most obvious effects from Vesugen administration. These systems include the central nervous system and cardiovascular system. Vesugen appears to play a prominent role in regulating sirtuin 1 protein levels. Sirtuin 1 has important effects on metabolic processes and helps to reduce the effects of aging. Sirtuin 1 is activated as a result of calorie restriction and is therefore thought to be one of the proteins responsible for the profound anti-aging effects associated with calorie restriction. ...
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Basic Info. Vesilute is a Khavinson bioregulator peptide with research exploring its role in regulating the urinary tract and prostate gland. Research evidence indicates that Vesilute may help to relieve symptoms associated with bladder and urinary tract dysfunction. Vesilute and other cytomedines have been shown to reduce prostate dysfunction and are thought to act by improving microcirculation in the prostate and by reducing cell proliferation. The latter effect may be due to changes in chromosome density and epigenetic factors, a mechanism of cellular regulation that is common among Khavinson peptides. ...
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Basic Info. Vilon is a potent immunomodulator and anti-aging bioregulator peptide with ample research to back its benefits. There are also high levels of evidence that Vilon may help prevent/reduce the risk of cancer development and progression. Research has shown that Vilon appears to provide better anti-aging effects when administered early in life. These findings may help open the door to better anti-aging research and help scientists to better understand how epigenetic regulation plays an important role in longevity. ...
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Basic Info. Testagen is a short, bioregulatory peptide that has primary effects on the pituitary gland and ultimately the thyroid gland. As a result of its action on these two glands, Testagen is capable of normalizing testosterone production as well as thyroid hormone production in certain settings. By normalizing thyroid hormone production, Testagen has a moderate impact on the immune system. In these cases, Testagen can be conveniently thought of as resetting the pituitary gland to a more youthful state and thereby acting as an anti-aging peptide. Testagen is being researched for its ability to boost testosterone levels, improve thyroid hormone function, and stimulate the differentiation of stem cells in the immune system to improve immune function. ...
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Basic Info. Adamax, an analogue of Semax, has a adamantane portion similar to P21. Over time, Adamax can help humans improve endurance, speed recovery from strenuous exercise, and stimulate brain activity. Due to its unique adamantane composition and increased bioactive stability after crossing the blood-brain barrier (BBB), Adamax improves the endurance of athletes by 2-3 times more than other Semax analogs. It increases brain-derived neurotrophic factor (BDNF) levels and enhances hippocampal TrkB receptor sensitivity. ...
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Basic Info. Acetyl hexapeptide-8 is a synthetic peptide that is primarily used in skin care products. Formerly known by its original trade name Argireline and generically as acetyl hexapeptide-3, it has water-binding properties and skin-restoring abilities that play roles in helping skin look and feel younger. Acetyl hexapeptide-8 is a neurotransmitter-inhibiting peptide, meaning it works within skin’s surface layers to interrupt the look of expression lines; however, its efficacy in this regard doesn’t replace in-office wrinkle-smoothing injectable procedures. Interestingly, research from suppliers has shown this peptide also helps support skin’s collagen and preserve a firmer appearance. Studies have shown this peptide can penetrate further into skin and delivery greater efficacy for smoothing expression lines if specific formulary steps are followed, including accounting for the type of emulsion (a higher water content allows greater penetration). As always, this demonstrates the importance of selecting well-formulated skin care products to add to your routine. ...
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Basic Info. Argipressin acetate, also known as arginine vasopressin (AVP), is a peptide hormone with antidiuretic and vasoconstrictive properties. It plays a crucial role in regulating fluid balance and blood pressure. In medical settings, it's used to treat conditions like diabetes insipidus and bleeding from esophageal varices. ...
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Basic Info. Cetrorelixis a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not ready for fertilization to be released. Cetrorelix does not allow the premature release of these eggs to occur. ...
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Basic Info. Exenatide is a 39 amino acid peptide derived from the salivary gland of the Gila monster. It is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Exenatide mimics the actions of GLP-1, a natural hormone that regulates insulin secretion and glucagon, improving glycemic control. It can be administered subcutaneously either twice daily (Byetta) or once weekly (Bydureon BCise). ...
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Basic Info. Glucagon hydrochloride is a medication, primarily used to treat severe hypoglycemia (low blood sugar) in individuals with diabetes, particularly those taking insulin. It also serves as a diagnostic aid in gastrointestinal imaging, helping to relax the stomach and bowel muscles for improved visualization. ...
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Basic Info. Selank and Semax are synthetic heptapeptides often used together for their potential to improve brain health and function. They are considered melanocortin stimulating hormone-like peptides and are available as nasal sprays or injections. ...
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Basic Info. GHK-Cuis a tripetide . During wound healing, Copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration. ...
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Basic Info. SNAP-8 peptide, or Acetyl Glutamyl Heptapeptide-1, is an advanced neuropeptide derived from Argireline(Acetyl Hexapeptide-3) . It was designed to enhance the wrinkle-reducing effects of Argireline while providing an even more potent ability to inhabit muscle contractions that cause expression lines. As part of the peptides in the skincare category. SNAP-8 works by reducing the depth of wrinkles caused by facial movements, such as frowning, smiling, or squinting. Scientifically, SNAP-8 functions by mimicking a fragment of the SNAP-25protein , which plays a crucial role in neurotransmitter release . It competes with natural SNAP-25 for a spot in the SNARE complex , thereby destabilizing the formation of synaptic vesicles responsible for muscle contractions. This mechanism effectively leads to a muscle-relaxing effect, similar to Botox but without injection-related risks. Over time, this helps prevent the deepening of fine lines and wrinkles , particularly on the forehead and around the eyes. ...
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Basic Info. Dihexa, also known as N-hexanoic acid-tyrosine-isoleucine-(6)-aminohexanamide, is an oligopeptide drug and an angiotensin IV analog. It is orally active and can penetrate the blood-brain barrier. It has a high affinity for hepatocyte growth factor (HGF) and enhances the activity of its receptor c-Met. Dihexa has shown excellent antipsychotic activity and cognitive improvement in animal models and has the potential to study and treat Alzheimer's disease. ...
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Basic Info. Vasoactive Intestinal Peptide (VIP) is a neuropeptide with a wide range of functions, including vasodilation, regulation of smooth muscle activity, and control of epithelial cell secretion. It acts as a neuromodulator and neurotransmitter in the gastrointestinal tract and other tissues. VIP is also involved in immune regulation, potentially playing a role in anti-inflammatory effects. ...
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Basic Info. FOXO4-DRI is a peptide designed to target and eliminate senescent cells, which accumulate with age and contribute to various age-related diseases and tissue damage. FOXO4-DRI works by selectively inducing apoptosis (programmed cell death) in senescent cells, effectively clearing them from the body. This mechanism can help restore tissue health and function by removing the negative influence of senescent cells. ...
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Basic Info. FTPP Adipotide is a research peptide known for its potential in targeting and reducing fat deposits. It functions as an experimental pro-apoptotic peptide, designed to selectively bind to blood vessels supplying white adipose tissue, leading to fat cell depletion. By disrupting the blood flow to fat cells, FTPP induces apoptosis (programmed cell death), causing a reduction in fat mass. Originally investigated for its potential in obesity research, FTPP has demonstrated promising results in animal studies, where it led to significant weight loss without affecting lean muscle mass. Researchers have explored its applications in metabolic health, fat loss studies, and obesity-related conditions. ...
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Basic Info. ARA-290, also known as cibinetide, is a non-hematopoietic peptide derived from erythropoietin. It's designed to activate the Innate Repair Receptor (IRR) and reduce inflammation by inhibiting the production of pro-inflammatory cytokines like TNFα. ARA-290 has shown promise in preclinical and clinical studies for treating conditions like type 2 diabetes, neuropathy, sarcoidosis, and age-related frailty. ...
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Basic Info. Aviptadil is a vasoactive pulmonary artery (VIP) analogue with strong vasodilatory effects. Aviptadil induces pulmonary vasodilation and inhibits vascular SMCs ischemia and ischemia. Aviptadil can be used in the study of pulmonary fibrosis, pulmonary arterial hypertension (PAH), and respiratory ischemia caused by SARS-CoV-2. It is also a vasoactive intestinal peptide (VIP) analogue with strong vasodilatory effects. Aviptadil induces pulmonary vasodilation, inhibits the proliferation of vascular SMCs and platelet aggregation. Aviptadil can be used for research on pulmonary fibrosis, pulmonary arterial hypertension (PAH), respiratory failure caused by SARS-CoV-2, etc. Aviptadil is a peptide composed of 29 amino acids. ...
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Basic Info. Bronchogen is a peptide that shows promise in supporting respiratory health, particularly for conditions affecting the bronchi. Studies suggest it may help reduce inflammation, promote tissue repair, and improve lung function in diseases like bronchitis, asthma, and COP D. ...
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Basic Info. B7-33 is a novel, synthetic compound that was first discovered and developed by a team of researchers at the Monash University in Australia. The development of B7-33 was based on the discovery of the relaxin receptor 1 (RXFP1) and the recognition of its potential as a therapeutic target for a wide range of diseases and conditions. The research team, led by Professor David Handelsman, first synthesized B7-33 in the early 2010s as part of their efforts to develop a functionally selective agonist for RXFP1. This compound was then tested in a series of in vitro and in vivo studies, which demonstrated its potential as a treatment for hypertension, kidney disease, and heart failure. The team's research on B7-33 was published in several scientific journals, including the Journal of Biological Chemistry and the Journal of Hypertension. These publications highlighted the compound's unique mechanism of action and its potential as a treatment option for patients. ...
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Basic Info. Cardiogen peptide likely refers to cardiac peptides, which are proteins secreted by the heart and blood vessels. These peptides play a crucial role in maintaining cardiovascular health and can be involved in the development of heart failure. Specifically, natriuretic peptides like atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are key cardiac peptides, and their levels can be measured in blood to help diagnose and monitor heart failure. ...
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